Publications

Here lies all of this lab's publications by order of date. Click on the title of the paper to get more information about a publication, including the abstract, date of publication, and open access link if applicable.

Age-specific functional epigenetic changes in p21 and p16 in injury-activated satellite cells.

The regenerative capacity of muscle dramatically decreases with age because old muscle stem cells fail to proliferate in response to tissue damage. Here, we uncover key age-specific differences underlying this proliferative decline: namely, the genetic loci of cyclin/cyclin-dependent kinase (CDK) inhibitors (CDKIs) p21 and p16 are more epigenetically silenced in young muscle stem cells, as […]