Time and entropy are not the sole decisive factors in aging.
The interconnected research venues pursued in the lab help to understand how the process of tissue repair is controlled, why the injured tissues are not productively repaired as we age; and to establish approaches that restore the regenerative potential both to the aged organ stem cells and transplanted cells exposed to the aged organ environments.
We focus on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, directed organogenesis, and making CRISPR a therapeutic reality.
We typically assay all three germ layer tissues, e.g. brain, muscle and liver.