• Skip to primary navigation
  • Skip to main content

The Conboy Laboratory

Engineering Longevity

  • Home
  • About
  • The Lab
    • Members
    • Past Members
  • Research
    • Discoveries & Projects
  • Science Publications
  • Patents
  • Entrepreneurship
  • Contact and Jobs

CRISPR-Gold fixes Duchenne muscular dystrophy mutation in mice

In the new study, research lead by the laboratories of Berkeley bioengineering professors Niren Murthy and Irina Conboy demonstrated that their novel approach, called CRISPR-Gold because gold nanoparticles are a key component, can deliver Cas9 – the protein that binds and cuts DNA – along with guide RNA and donor DNA into the cells of a living organism to fix a gene mutation.

“CRISPR-Gold is the first example of a delivery vehicle that can deliver all of the CRISPR components needed to correct gene mutations, without the use of viruses,” Murthy said.

The study was published October 2 in the journal Nature Biomedical Engineering.

See More

Copyright © 2023 · Berkeley CoE Theme on Genesis Framework · WordPress · Log in